| 释义 |
dopamine Biochem.|ˈdəʊpəmiːn|
[f. dopa + amine.]
The immediate precursor of noradrenaline in the body, found esp. in nervous and peripheral tissue and formed by decarboxylation of dopa; 3,4-dihydroxyphenylethylamine, C8H11NO2.
1959Senoh & Witkop in Jrnl. Amer. Chem. Soc. LXXXI. 6222/1 This investigation concerns itself with related hydroxylation mechanisms of 3,4-dihydroxyphenethylamine (‘dopamine’), a biogenic amine of key importance in metabolism. 1962J. H. Burn Drugs, Med. & Man xi. 115 When dopa enters the brain the substance dopamine is..formed. 1965New Scientist 18 Mar. 719/1 Three of the key monoamines are noradrenaline, dopamine and 5-hydroxytryptamine. 1969New Scientist 30 Oct. 234/2 It is thought that if dopamine is absent, there is no way of checking the excitatory action of the ACh in the caudate nucleus, and that this..results in tremor and rigidity of the muscles. 1971Nature 7 May 54/1 The principal biochemical defect associated with Parkinsonism is a marked decrease in the dopamine and serotonin content of the brain. |