| 释义 |
synapto-|sɪˈnæptəʊ|
ad. Gr. συναπτ-ικός, connective, used as comb. form of synapse, in various terms in Physiol., as synaptoˈgenesis, the formation of synapses between nerve cells; synapˈtology, the study of the structure and operation of synapses; syˈnaptosome [-some4], a presynaptic nerve ending which, when isolated, seals up to form an intact sac; hence synaptoˈsomal a.
1967D. P. Purpura in A. Minkowski Regional Devel. of Brain in Early Life 131 We started this morning with looking at myelinogenesis, moved to cytoarchitectonics, and started talking about the probable growth of dendrites. You have now moved us into a fourth area of maturational considerations— that of synaptogenesis. 1979Experientia XXXV. 207/1 Intracerebellar connections are gradually established as the synaptogenesis proceeds.
1962Anat. Rec. CXLII. 332/2 (heading) An electron microscope study of the stratum radiatum of the rat hippocampus..with emphasis on synaptology. 1965Sci. Amer. Jan. 56/3 Sir Charles Sherrington..laid the foundations of what is sometimes called synaptology. 1975Nature 8 May 176/2 There have been great advances in knowledge of synaptology from electron microscopic studies of the retina.
1970Neurosciences Res. III. 6 There is more than a sixfold increase in the ATPase activity of the rat brain nerve-ending fraction from prenatal to the 10-day-old animal, the enzyme apparently residing in the synaptosomal limiting membrane. 1978Nature 17 Aug. 706/2 The crude synaptosomal pellet was resuspended in 0·32 M glucose..and equilibrated..in a rotary waterbath.
1964V. P. Whittaker et al. in Biochem. Jrnl. XC. 293/1 The club-like presynaptic nerve endings resist disruption and are snapped or torn off from their attachments to form discrete particles (nerve-ending particles) in which all the main structural features of the nerve ending are preserved. For these particles we propose the name ‘synaptosomes’ in order to emphasize their relative homogeneity and their resemblance in physical properties to other subcellular organelles. 1973Nature 9 Mar. 122/1 Isolation of intact synaptic nerve endings (synaptosomes) had made it possible to investigate transport across synaptic membranes. |