| 释义 |
taxane, n. Chem.
Brit. |ˈtakseɪn|, U.S. |ˈtækˌseɪn|
[‹ scientific Latin Taxus, genus name (> adj.) + -ane suffix.]
Any of a class of tricyclic terpenoid compounds isolated from certain trees and shrubs of the genus Taxus (the yews), or prepared synthetically; (also) a hydrocarbon having the C20 molecular skeleton present in these compounds.
1964B. Lythgoe et al. in Proc. Chem. Soc. 301/2 These constituents belong to a new type of diterpenoid, and since undoubtedly other compounds having the same skeleton exist in the plant, we suggest the name ‘Taxane’ for the nucleus. 1971Ann. Rep. Delegates Sci. Area Univ. Oxf. 29 The isolation of seven new taxane derivatives from the heartwood of yew. 1994Nature 17 Feb. 593/1 Its [sc. taxol's] attraction to pharmacologists was its unique structure, a complex diterpenoid containing the taxane ring system and a rare four-membered oxetane ring and ester side chain, that suggested the possibility of a new mechanism for an anti-tumour drug. 2000New Scientist 13 May 7/3 Theryte..describes a test to determine which chemotherapy agent is best for treating a particular tumour: chemotherapy with cis-platinum or taxanes such as taxol. |