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单词 adrenocorticotrophic
释义 adrenocorticotrop(h)ic, a.|æˈdriːnəʊˌkɔːtɪkəʊˈtrɒfɪk, -ˈtrɒpɪk|
[f. adreno- + cortico- + trophic a.]
Stimulating or controlling the adrenal cortex; esp. adrenocorticotrop(h)ic hormone (abbrev. A.C.T.H.), a hormone produced by the pituitary gland which influences the action of the adrenal cortex.
1936Proc. Soc. Exp. Biol. & Med. XXXV. 281 (title) Effect of Adrenocorticotropic Extracts on Accessory Reproductive Organs of Castrate Rats.1937Ibid. 649 Preparation and biological assay of adrenocorticotropic hormone.1938J. D. Reese & H. D. Moon in Anatomical Rec. LXX. 543 The..increase in the adrenal of normal rats following administration of the adrenocorticotrophic hormone of the anterior hypophysis is well known.1944Anatomical Rec. LXXXIX. 163 Effect of adrenocorticotropic hormone (ACTH) on the anterior pituitary of the adrenalectomized young male rat.1950Lancet 7 Jan. 11/1 A.C.T.H. seems to be the most promising tool medical investigators have today.1962Lancet 28 Apr. 888/1 Acute failure was precipitated by the adrenocorticotrophic stimulus of isoniazid.
Hence aˌdrenocorticoˈtrop(h)in [-in1] = adrenocorticotrop(h)ic hormone.
1952Proc. Soc. Exp. Biol. & Med. LXXIX. 252 (title) Cytologic Changes in Rat Adenohypophysis Following Administration of Adrenocorticotrophin or Cortisone.1959New Biol. XXVIII. 131 Some tumours of the pituitary gland secrete abnormally large amounts of a hormone, adrenocorticotrophin, known as ACTH for short, which is required for the normal maintenance and function of the adrenal cortex.
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