| 释义 |
tetracosactrin Pharm.|ˌtɛtrəkɒˈsæktrɪn|
[f. tetra- + icos- + adrenocorticotrophin.]
A synthetic polypeptide (see quot. 1967) which resembles corticotrophin in its action and uses but lacks its antigenic property, and is given (as the acetate) by injection in the long-term treatment of inflammatory and degenerative disorders.
1967Brit. Med. Jrnl. 18 Nov. 391/1 Tetracosactrin (β1-24 corticotrophin, Synacthen) is a synthetic poly⁓peptide containing the first 24 amino-acids found in naturally occurring corticotrophin (A.C.T.H.). 1972Ibid. 11 Mar. 680/1 The pathognomic finding is their failure [sc. that of urinary and plasma corticosteroids] to show a rise after the administration of ACTH or tetracosactrin. 1979Jrnl. R. Soc. Med. LXXII. 530 A tetracosactrin (Synacthen) stimulation test. |