| 释义 |
fumigacin Biochem.|fjuːmɪˈgeɪsɪn, fjuːˈmɪgəsɪn|
[f. mod.L. fūmigā-tus (see fumigatin) + -cin as in actinomycin: see -in1.]
a. An antibiotic produced by the fungus Aspergillus fumigatus, now considered to be a mixture of the antibiotics helvolic acid and gliotoxin.
b. = helvolic acid.
1942[see clavacin]. 1944Jrnl. Biol. Chem. CLII. 429 The crystalline material formerly described as fumigacin is a mixture of fumigacin and gliotoxin. Pure fumigacin..appears to be identical with the helvolic acid recently isolated. 1949H. W. Florey et al. Antibiotics I. vii. 333 Fumigacin..appeared to differ..from helvolic acid. Further investigations.. showed that fumigacin was, in fact, a mixture of helvolic acid and gliotoxin. 1953J. Ramsbottom Mushrooms & Toadstools xxiii. 289 Fumigacin (helvolic acid)..has all the necessary qualities except that bacteria readily acquire resistance to it. 1959[see clavacin]. |