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单词 tyrocidine
释义 tyrocidine Pharm.|taɪrəʊˈsaɪdɪn, -diːn|
Also tyrocidin.
[f. mod.L. Tyro-thrix (see tyrothricin) + -cide + -in1, -ine5, after gramicidin.]
(Any of) a group of crystalline monocyclic decapeptide antibiotics which along with the gramicidins are the active components of tyrothricin, as tyrocidine A (C66H87O13N13), tyrocidine B (C68H88O13N14), tyrocidine C (C70H88O13N15).
1940Hotchkiss & Dubos in Jrnl. Biol. Chem. CXXXVI. 803 This substance was described earlier under the name graminic acid before its low chlorine content was recognized; it will be referred to hereafter as tyrocidine hydrochloride.1952Battersby & Craig in Jrnl. Amer. Chem. Soc. LXXIV. 4021/2 Crystalline tyrocidine hydrochloride is in fact a family of polypeptides... The major peptides have been called tyrocidine A, tyrocidine B, tyrocidine C according to their partition ratios in the solvent system.1969Tyrocidin [see gramicidin].1977J. S. Glasby Encycl. Antibiotics 350/1 Most of the bacteriological examination has been carried out on the mixture of tyrocidins.
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