| 释义 |
gnoscopine Chem.|ˈnɒskəpiːn, -ɪn|
[irreg. f. Gr. γι-γνώσκ-ειν to know + opium + -ine5.]
Either of two isomeric alkaloids, C22H23NO7, designated α- and β-gnoscopine, of which α-gnoscopine is found in opium and β-gnoscopine obtained synthetically.
1878T. & H. Smith in Pharm. Jrnl. & Trans. 3rd Ser. IX. 82/1 In the mother liquors from the purification of narceine we have now repeatedly met with a crystalline body, which..was..ascertained to be a hitherto unknown alkaloid, and which we have named Gnoscopine. 1914Hope & Robinson in Jrnl. Chem. Soc. CV. ii. 2087 It is proposed to call the substance melting at 180° β-gnoscopine, reserving the name α-gnoscopine for the compound previously known as gnoscopine or r-narcotine, which melts at 229°. 1951A. Grollman Pharmacol. & Therapeutics iv. 88 The remaining [opium] alkaloids (laudanosine,..codamine, gnoscopine, etc.) occur in too small quantity to have any influence on the action of the crude drug. 1954Stanek & Manske in Manske & Holmes Alkaloids IV. xxxii. 181 Both of the gnoscopines were convertible into narceine, indicating that the only differences were stereochemical ones, and β-gnoscopine was partly isomerized to α-gnoscopine. |