| 释义 |
guanase Biochem.|ˈgwɑːneɪz, -s|
[a. G. guanase (Jones & Partridge 1904, in Hoppe-Seyler's Zeitschr. f. physiol. Chem. XLII. 347), f. guanine + -ase.]
An enzyme that hydrolyses guanine to xanthine and ammonia; guanine aminohydrolase, guanine deaminase.
1904Jrnl. Chem. Soc. LXXXVI. i. 838 Fresh pancreas, when subjected to autolysis, does not yield adenine or guanine, and guanine which is added is transformed into xanthine within 3 days. The enzyme present in pancreas which induces this change is termed Guanase. 1967Biochem. Jrnl. CIV. 634/1 Guanase (guanine aminohydrolase, EC 3.5.4.3) was of special interest as guanine is metabolically a precursor of xanthine and is thus indirectly a source of uric acid. |