| 释义 |
homocysteine Chem.|hɒməʊˈsɪstiːn, -ˈsɪstiːɪn|
[f. homo- b + cysteine.]
An amino-acid, HS·CH2·CH2·CH(NH2)·COOH, which is important as an intermediate in the metabolism of methionine and cysteine.
1932Jrnl. Biol. Chem. XCIX. 137 If the hydrolysis, however, should take place between the methyl group and the sulfur then methyl alcohol and homocysteine would result. 1935Ibid. CXII. 149 (heading) The isolation of homocysteine and its conversion to a thiolactone. 1962Biochem. & Biophys. Res. Comm. IX. 493 The normal pathway for the metabolism of methionine involves demethylation to homocysteine which in turn combines with serine to form cystathionine, an intermediate along the pathway to cysteine and cystine. |