| 释义 |
vacuolating, ppl. a. Med.|ˈvækjuːəleɪtɪŋ|
[Back-formation from vacuolation: see -ing2.]
vacuolating agent or vacuolating virus: a papovavirus, orig. obtained from rhesus monkey kidney tissue, which is capable of causing tumours in animals and animal tissue cultures; also called SV 40 (cf. SV s.v. S 4 a); also, a virus related to this.
1960Sweet & Hilleman in Proc. Soc. Exper. Biol. & Med. CV. 420/1 This agent has been called the ‘vacuolating virus’ by us because of the prominent cytoplasmic vacuolation seen in infected cell cultures... The discovery of this new virus, the vacuolating agent, represents the detection..of a hitherto ‘non-detectable’ simian virus of monkey renal cultures. 1965Listener 11 Mar. 369/2 A remarkable situation is also presented by..vacuolating virus or simian virus 40. This virus..was accidentally given to millions of human subjects with early batches of polio vaccine. 1977Jrnl. Virology XXI. 179/1 Papovaviruses of the simian virus 40 (SV 40)-polyoma subgroup..occur in the mouse.., the rabbit (rabbit kidney vacuolating virus [RKV]), [etc.]. |