| 释义 |
imidazole Chem.|ɪˈmɪdəzəʊl|
[ad. G. imidazol (Hantzsch & Weber 1887, in Ber. d. Deut. Chem. Ges. XX. 3119), f. imid imide + azo- + -ol -ole.]
a. A colourless, crystalline, heterocyclic compound consisting of the five-membered ring NH{b1}CH{b2}N{b1}CH{b2}CH. Also called glyoxaline.
b. Any of the derivatives of this compound.
1892Jrnl. Chem. Soc. LXII. 313 Derivatives obtained by displacing a CH group in these by N are designated imidazole = C3H3(NH)N, oxazole = C3H3(O)N, and thiazole = C3H3(S)N respectively. 1900E. F. Smith tr. V. von Richter's Org. Chem. (ed. 3) II. 480 The glyoxalines or imidazoles. 1936L. J. Desha Org. Chem. xxiv. 493 Pyrazole and imidazole, C3H4N2, are isomers differing in the relative positions of the nitrogen atoms. 1946[see glyoxaline]. 1951A. Grollman Pharmacol. & Therapeutics xi. 216 Certain imidazole derivatives also exert actions similar in some respects to the sympathetic amines. 1953R. H. Wiley in H. Gilman Org. Chem. IV. viii. 787 The imidazole nucleus is found naturally in the amino acid histidine..; in the purines..; in biotin..; and in histamine. 1968[see glyoxaline]. 1968L. A. Paquette Princ. Mod. Heterocyclic Chem. vi. 185 Imidazole and pyrazole..readily form salts with metal ions. |