| 释义 |
vincristine Pharm.|vɪnˈkrɪstiːn|
[f. as vinblastine + leuco)cristine (former name of the drug), perh. f. leukaemia + -ro- + crista + -ine5.]
A cytotoxic alkaloid, C46H56N4O10, obtained from the periwinkle Catharanthus roseus and administered intravenously (usu. as the sulphate) in the treatment of acute leukæmia and other cancers.
1962M. R. Karon et al. in Pediatrics XXX. 791 (heading) A preliminary report on vincristine sulfate—a new active agent for the treatment of acute leukemia. 1977Lancet 19 Feb. 433/1 Complete remission [of acute lymphocytic leukæmia] was achieved on a regimen of vincristine, prednisone, and daunomycin. 1983[see vinblastine]. |