| 释义 |
proline Biochem.|ˈprəʊliːn|
Formerly also prolin.
[ad. G. prolin (Fischer & Suzuki 1904, in Ber. d. Deut. Chem. Ges. XXXVII. 2843), contraction of pyrrolidin pyrrolidine.]
A colourless, crystalline amino-acid, pyrrolidine-2-carboxylic acid, C5H9NO2, the lævorotatory form of which is a constituent of most proteins.
1904Jrnl. Chem. Soc. LXXXVI. i. 917 (heading) Derivatives of prolin. Ibid., The proline used was derived from gelatin. 1911Jrnl. Biol. Chem. IX. 205 Prolin is ordinarily determined in the ester hydrolysis by alcoholic extraction of the amino-acids whose esters boil below 90° at less than 1 mm. pressure. 1913Ibid. XIII. 513 Proline, when added to blood used for perfusing a surviving dog's liver, leads to no increase in the normal formation of acetoacetic acid, nor is the acetoacetic acid excretion of glycosuric animals markedly increased by the administration of proline. 1946Nature 5 Oct. 474/2 All the proline residues appear to be situated at points roughly one third and two thirds along the length of the molecule. 1954A. White et al. Princ. Biochem. vii. 109 Proline is present in all proteins which have been studied. 1973Biggs & Woodson Clin. Biochem. iii. 38 All amino acids—with the exception of proline, which has an imino group—have an amino group on the α carbon. |