| 释义 |
labilize, v. Chem. and Biochem.|ˈleɪbɪlaɪz|
[f. labile a. + -ize.]
trans. To render labile (esp. a chemical bond). So ˈlabilizing ppl. a. and vbl. n.
1903Nature 26 Feb. 385/2 The rôle of the oxygen must have been that of a labilising agent. 1938Jrnl. Biol. Chem. CXXV. 1 These and other polar groups..may conceivably labilize adjacent carbon-bound hydrogen atoms. 1957New Biol. XXIII. 77 Proteins could also have become radioactive by an exchange reaction in which two peptide bonds in the chain of a protein are labilized, allowing an amino acid held at this point to be exchanged with another molecule of the same amino acid present in the surrounding medium. 1962Biochem. Pharmacol. IX. 113 Stabilization disappears and is replaced by a labilizing influence. 1972European Jrnl. Biochem. XXVI. 540/1 Free lysosome enzymes can labilize lysosomal membrane. 1973Chem. Soc. Rev. II. 177 The factor responsible for a high labilizing ability depends on this mechanism.
Hence ˌlabiliˈzation, the process of rendering or becoming labile; ˈlabilizer, a labilizing agent.
1938Jrnl. Biol. Chem. CXXV. 19 Stekol and Hamill..have claimed that proteolytic enzymes can carry out such a labilization. 1956Radiation Res. V. 263 The increased susceptibility of X-irradiated DNP to the action of trypsin is not inconsistent with the concept of a labilization of the DNA-to-protein salt-like secondary linkages. 1965Dissertation Abstr. XXV. 4355/2 It is concluded that the labilization of the carboxyl carbon of glycine is a discrete reaction which can be measured independently of reactions related to further metabolism of the α-carbon. 1967Pike & Brown Nutrition vii. 145 Other labilizers of the lysosomal membrane are ultraviolet light and ionizing radiation. 1974Nature 13 Dec. 579/1 The labilisation of the ligand trans to an oxo group is a well known effect. |