| 释义 |
lactulose, n. Biochem. and Pharm.|ˈlæktjʊləʊz|
[f. lacto- + -ul- + -ose2, perh. after cellulose a. and n.]
A synthetic disaccharide of fructose and galactose that is given as a laxative; 4-O-β-d-galactopyranosyl-d-fructose, C12H22O11 .
Orig. (Science (1929) 24 May 556/2) called lactoketose.
1930Montgomery & Hudson in Jrnl. Amer. Chem. Soc. LII. 2101 The name lactoketose was..used for the sugar but it has been decided subsequently to name it lactulose. 1938M. L. Wolfram in H. Gilman Org. Chem. I. xvi. 1442 The Lobry de Bruyn dilute alkali interconversion reaction was used..in obtaining the crystalline ketose of lactose (lactulose). 1983Oxf. Textbk. Med. I. xii. 14/2 Lactulose..is useful in patients whose colons are full of hard scybala as it softens the stool partly by an osmotic effect and partly by the production of lactic acid and other organic acids. 1989Martindale's Extra Pharmacopoeia (ed. 29) 1093 Lactulose is a synthetic disaccharide which is used in the treatment of..hepatic encephalopathy. 1991Lancet 7 Sept. 633/1 For three weeks before admission she had been taking terodiline 25mg twice daily plus lactulose and ‘Fybogel’. |