| 释义 |
androstenedione, n. Physiol.|ˌændrɒstiːnˈdaɪəʊn|
[ad. G. Androstendion (coined by Ruzicka & Wettstein 1935, in Helv. Chim. Acta XVIII. 988): see androsterone n., -ene, -dione.]
An androgenic steroid, C19H26O2 , from which testosterone and certain oestrogens are derived in humans.
1935Nature 17 Aug. 259/1 The table clearly shows the high activity of androstendione [sic] on the seminal vesicles and the penis. 1959S. L. Simpson Major Endocrine Disorders (ed. 3) ii. 80 The two important adrenal androgens in man are 11β-hydroxy Δ4-androstene-3-17-dione and Δ4-androstenedione. 1964L. Martin Clin. Endocrinol. (ed. 4) viii. 263 The normal ovarian theca-cell contains all the enzymes needed for the conversion of progesterone to oestradiol, an intermediate stage being the substance androstenedione. 1988L. Stryer Biochem. (ed. 3) xxiii. 568 The side chain consisting of C-20 and C-21 is then cleaved to yield androstenedione, an androgen. |