| 释义 |
leptin, n. Biochem.
Brit. |ˈlɛptɪn|, U.S. |ˈlɛptən|
[‹ ancient Greek λεπτός thin + -in suffix1.]
A protein, originally identified as the product of the ob gene in mice and later found in humans and other species, which is expressed only in adipose tissue and is involved in the regulation of appetite and fat storage.
1995J. L. Halaas et al. in Science 28 July 546/1 Because a principle [sic] action of the OB protein is to make an animal thinner, we propose that this 16-kD protein be called leptin, derived from the Greek root leptós, meaning thin. 1996Independent 9 Dec. i. 18/3 Massively fat, diabetic and infertile: it's no fun being a mouse deficient in leptin. 1999J. Elkington & J. Hailes New Foods Guide v. 245 Amgen, a leading American biotechnology firm, has been working on a new drug, based on protein called leptin, which would persuade the brain to switch off the appetite sooner than normal. 2000Internat. Jrnl. Obesity 24 906 Changes of fullness were also associated with changes of fasting leptin in men. |