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单词 loperamide
释义 loperamide, n. Pharm.|ləʊˈpɛrəmaɪd|
[Prob. f. chloro-2 + piperidine n. + amide n.]
An opiate drug, C29H33N2O2Cl , which inhibits peristalsis and is given orally as the hydrochloride in the treatment of diarrhoea.
1971WHO Chron. XXV. 425 Loperamide.1976Gastroenterology LXX. 1026/1 Loperamide specifically inhibits peristaltic activity by its direct effect on the gastrointestinal wall.1980Lancet 26 Jan. 209/1 A further argument against the use of loperamide is that it may induce ileus in children.1987Brit. Med. Jrnl. 28 Feb. 555/1 The regular use of loperamide would be advisable since it is often effective in reducing frequency of defecation.1994L. A. Graf Traitor Winds xvii. 236 Trazadone hydrochloride, dextromethorphan, loperamide, sodium salicylate... Vial after vial sported labels.
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