| 释义 |
melphalan, n. Pharm.|ˈmɛlfəˌlæn|
[f. methyl n. + L 8 c (ii) + phenylalanine n.]
A nitrogen mustard given intravenously in the treatment of myelomatosis and other neoplasms; 4-bis(2-chloroethyl)amino-l-phenylalanine, C13H18N2O2Cl2 .
1960Cancer Chemotherapy Rep. Feb. 61 Melphalan. 1962Surgery LI. 583/1 Phenylalanine mustard exists in two forms. One is the dl form called Sarcolysin; the other is the l form called melphelan [sic]. 1974R. M. Kirk et al. Surgery v. 73 When excision is not possible..it is worth trying the effects of..systemic chemotherapy with phenylalanine mustard drugs, or melphalan given systemically. 1977Lancet 18 June 1307/1 In our similar studies of 8 patients menstruating regularly plasma œstradiol and androgens were measured frequently at random before and after five-day pulses of melphalan. 1992Sci. News 27 June 420/2 Melphalan, seldom used anymore in adjuvant therapy, poses roughly 10 times the leukemia risk. |