| 释义 |
mercapturic, a. Chem.|mɜːkæpˈtjʊərɪk|
[ad. G. bromphenyl)mercaptur(säure bromophenylmercapturic acid (Baumann & Preusse 1879, in Ber. d. Deut. Chem. Ges. XII. 807), f. mercapt(an mercaptan + ur(in urine n.1: see -ic.]
mercapturic acid: any of the acids of the formula RSCH2CH(NH·CO·CH3)COOH (where R is an aryl radical), some of which are excreted in the urine, probably as detoxication products of aromatic compounds.
1879Jrnl. Chem. Soc. XXXVI. 803 An examination of the urine of a dog, to which 3 to 4 grams of bromobenzene had been daily administered for six months, showed... The urine contains bromophenyl-mercapturic acid. 1884Ibid. XLVI. 1395 A body strongly lævorotatory, which on treatment with acids yields mercapturic acid. 1934Times Lit. Suppl. 9 Aug. 555/2 Naphthalene is detoxicated in the rabbit partly by conjugation with cysteine and subsequent excretion as the mercapturic acid. 1971H. G. Mandel in B. N. La Du et al. Fund. Drug Metabolism x. 168 Acetylation takes place in the liver..and the resulting mercapturic acid is then excreted in the urine. |