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单词 metoprolol
释义 metoprolol, n. Pharm.|mɪˈtɒprəlɒl|
[f. meth + -o1 + propranolol n.]
A beta-adrenergic blocking agent which is given orally (usually as the tartrate) and intravenously in the treatment of hypertension and angina; 1-isopropylamino-3-p-(2-methoxymethyl)phenoxypropan-2-ol, C15H25NO3 .
1974Jrnl. Pharmacokinetics & Biopharmaceutics II. 363 The present study has shown that metoprolol, a new selective β1-receptor antagonist, is rapidly and completely absorbed when administered orally in solution.1977Lancet 16 Apr. 843/1 With metoprolol Davidson et al. found a rise in heart-rate with only a small and insignificant increase of diastolic pressure.1986C. W. Thornber in C. A. Heaton Chem. Industry iv. 173 Astra and Ciba-Geigy both sell metoprolol but under the trade marks Betaloc and Lopressor.1993Alert Driver Jan.–Feb. 9/2 Drugs designed to reduce or limit heart rate (Inderal, Labetalol, Metoprolol) could affect driver capacity.
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