| 释义 |
mitomycin Biochem.|maɪtəʊˈmaɪsɪn|
[f. mito- (perh. representing Gr. µίτος thread or mitosis, mitochondrion, etc.: the allusion is not explained by the (Japanese) authors of the name) + -mycin.]
An antibiotic active against some bacteria and tumour cells that is produced by the soil bacterium Streptomyces cæspitosus; also any of the three (or more) slightly different molecular species (as those designated mitomycin A, B, and C) into which preparations of this antibiotic can be resolved.
1956T. Hata et al. in Jrnl. Antibiotics (Tokyo) A. IX. 141 (heading) Mitomycin, a new antibiotic from Streptomyces. Ibid. 145 Mitomycins have a high antibacterial activity against gram positive and gram negative bacteria. 1958Antibiotics & Chemotherapy VIII. S[treptomyces] caespitosus, which produces mainly mitomycin A and B in some cultural conditions, produces mitomycin C exclusively under other conditions. 1968[see induction 9 d]. |