| 释义 |
muˈtator
[a. L. mūtātor, agent-noun f. mūtāre to change.]
†1. One who changes. Obs. rare—1.
1632[see plantator 1].
2. Biol. Any gene which increases the mutation rate of other genes. Usu. attrib., esp. in mutator gene.
1943Proc. Nat. Acad. Sci. XXIX. 138 In determining the abnormal mutation rate we shall consider only those cultures which have given at least one sex-linked recessive, since this is the only indication of the presence of the ‘Mutator’ gene in the mother. 1945Genetics XXX. 496 Recently, high mutation frequency in a strain of D. pseudoobscura, race B, was found to be due to a dominant mutator. 1970Jrnl. Molecular Biol. L. 129 Mutator genes cause a generalized increase in mutation rate. They have been identified in a variety of organisms, including phage and bacteria. |