释义 |
myasthenia gravis Med.|maɪəsˌθiːnɪə ˈgrævɪs| [mod.L., shortening of myasthenia gravis pseudoparalytica (F. Jolly 1895, in Berliner klin. Wochenschr. 7 Jan. 7/1), f. myasthenia + L. gravis severe, grave.] A rare chronic disease, occurring chiefly in young adults, that is characterized by muscular weakness unaccompanied by atrophy, with temporary paresis following exertion, and is caused by a defect in the mechanism which converts a nervous impulse into a muscular contraction.
1900Campbell & Bramwell in Brain XXIII. 278 The disease has received various names. The earlier cases were published as ‘cases of bulbar paralysis without discoverable anatomical changes’... Strümpell introduced the term ‘Asthenic bulbar palsy’... Other names which have been employed are ‘general profound myasthenia’, ‘Erb's disease’, the ‘Erb–Goldflam’ and the ‘Hoppe–Goldflam-symptom-complex’. Jolly has proposed the term ‘myasthenia gravis pseudo-paralytica’, and this, or for short ‘myasthenia gravis’, appears to us the most suitable and convenient hitherto suggested. 1939W. Haymaker tr. R. Bing's Textbk. Nerv. Dis. v. 182 Myasthenia gravis occasionally appears in more than one member of a family. 1961Lancet 5 Aug. 281/2 The clinical diagnosis of myasthenia gravis is usually easy. 1970Toronto Daily Star 24 Sept. 1/4 The twins have myasthenia gravis, a disease that killed their brother Richard last year when he was 6 months old. Excitement of any kind..can set off the choking, gasping attacks. 1974Passmore & Robson Compan. Med. Stud. III. xxxiv. 31/2 Myasthenia gravis is also associated with an immunological disturbance. |