| 释义 |
myeloma Path.|maɪəˈləʊmə|
Pl. -omas, -omata.
[f. myelo- + -oma.]
A tumour composed of bone-marrow cells (see quots.); spec. (a) (the tumour found in) myelomatosis; (b) a giant-cell sarcoma.
1857Mayne Expos. Lex. 736/1 Myeloma, term for a medullary tumour or enlargement. 1894Med. News (Philadelphia) LXV. 239/1 (heading) Myeloma: report of a case. 1900Dorland Med. Dict. 419/2 Myeloma, (1) any medullary tumor; (2) giant-cell sarcoma; (3) a slow-growing tumor of a tendinous sheath containing myeloplaxes. 1902Encycl. Medica XII. 449 Myelomata are rare tumours after the age of twenty-five. 1914Lancet 28 Nov. 1236/2 This large class [sc. giant-cell sarcoma] is made up of two groups of cases: (1) the myeloid sarcomata, myelomata of some authors; and (2) the malignant giant-cell sarcomata. 1922J. Ewing Neoplastic Dis. (ed. 2) xviii. 256 Giant-cell sarcoma of tendon sheaths and aponeuroses.—The specific structure and benign clinical course of a group of giant-cell sarcomas of tendon sheaths of the hand and feet have long been recognized. They have been fully described, especially by French observers, under the terms ‘myeloma’ or ‘xanthosarcoma’ (Gross, Paquet, Reverdin, Heurteaux, Spiess, Lit.). 1948R. A. Willis Path. Tumours xliii. 680 The changing views regarding the nature of this tumour [sc. osteoclastoma or giant-cell tumour of bone] have resulted in a diverse and confusing terminology—‘myeloma’, ‘myeloid sarcoma’, ‘tumeur à myéloplaxes’, ‘benign giant-cell tumour’, ‘osteoclastoma’, and ‘chronic (non-suppurative) hemorrhagic osteomyelitis’, being only some of the names applied to it. ‘Myeloma’ and ‘myeloid’ should be discarded, for the tumours are unrelated to the haemopoietic tumours of bone marrow, and in particular are quite distinct from the lesions of myelomatosis. 1966Wright & Symmers Systemic Path. I. iv. 185/2 Sometimes myelomas produce extramedullary masses in the viscera. 1967New Scientist 4 May 276/3 The other source of information..about antibody structure has been the discovery of diseases, called myelomas, in which molecules, chemically similar to the immune globulins but without known antibody activity, are produced in the blood of patients suffering from a cancer-like proliferation of cells in the bone marrow and bloodstream. 1970Passmore & Robson Compan. Med. Stud. II. xxviii. 4/2 An important tumour affecting the bone marrow is the plasma cell myeloma (myelomatosis or multiple myeloma). In this disease the bone marrow becomes packed with plasma cells. |