| 释义 |
paracrine, a. Physiol.|ˈpærəkriːn|
[ad. G. parakrin, f. Gr. παρα- para-1 + κρίν-ειν to separate (cf. endocrine a. and n.).]
Used of the action of a hormone whose effects are only local, and of the tissues which release and respond to such a hormone.
1972F. Feyrter in Endocrinol. 1971 137 The hypothesis of the peripheral entodermal endocrine (paracrine) glands was confirmed (1) by the evidence of a pressor agent in the enteral carcinoid.., (2) by the discovery of the islet cells of the pancreatic duct with A and B cells, their endocrine function having already been established. 1976Nature 8 July 92/3 The actions of this hormone are paracrine, directed that is to neighbouring cells and tissue, rather than truly endocrine. 1978Ibid. 20 Apr. 730/2 Further investigations related to the possible release of other endogenous substances or peptides, such as vasopressin or those of the paracrine system of the gut, where enkephalin immunoreactivity has been demonstrated, are needed. |