| 释义 |
pempidine Pharm.|ˈpɛmpɪdiːn|
[f. penta- + methyl + piperidine.]
An alkaline liquid, C10H21N, which has been used (usu. in the form of its hydrogen tartrate, a white, crystalline powder), as a ganglion-blocking agent in the treatment of severe hypertension; 1,2,2,6,6-pentamethylpiperidine.
1958Nature 21 June 1717/2 In the simple..tertiary amine, 1:2:2:6:6-pentamethylpiperidine.., for which the common name pempidine has been suggested, we have a potent ganglion-blocking drug. 1960Lancet 21 Jan. 143/2 In 1958 a new ganglion-blocking agent, pempidine tartrate, was made available under the trade names of ‘Perolysen’ and ‘Tenormal’. 1961Ibid. 12 Aug. 334/2 A Jamaican..was admitted to hospital and stabilised on pempidine and chlorothiazide. 1974Prescribers Jrnl. XIV. 47 Ganglion blocking drugs, such as pentolinium..and pempidine.., have been omitted from this short review because in the drug treatment of hypertension they have now been largely superseded. |