| 释义 |
Pendred Path.|ˈpɛndrɛd|
[The name of Vaughan Pendred (1869–1946), English physician who described the condition in 1896 (Lancet 22 Aug. 532).]
Pendred('s) syndrome: a recessively inherited condition in which an enzyme deficiency leads to goitre and usu. to deafness.
1960G. R. Fraser Deafness with Goitre (Syndrome of Pendred) (Ph.D. thesis, Univ. of London) 3 The name Pendred is suggested as a suitable eponym for this syndrome... A..study of sixty-two cases of Pendred's syndrome in forty-one sibships is described. 1966J. B. Stanbury et al. Metabolic Basis of Inherited Dis. (ed. 2) x. 234/2 The patients with the Pendred syndrome do not have large goiters. 1970J. F. Sotos in R. M. Goodman Genetic Disorders Man xvi. 666/1 In a few reports thyroid disease without deafness has occurred in relatives of patients with the Pendred syndrome. 1974J. D. Maynard in R. M. Kirk et al. Surgery xii. 250 Affected children are goitrous, hypothyroid, and sometimes deaf (Pendred's syndrome after the general practitioner who reported the first family in County Durham). |