| 释义 |
perˈsister
[f. persist v. + -er1.]
a. One who persists. rare.
1748Richardson Clarissa (1811) II. viii. 44 Each of them tends to the exclusion of that ungenerous persister's visits.
b. Biol. A bacterium which continues to live in the presence of enough antibiotic to kill almost all members of its species.
1944J. W. Bigger in Lancet 14 Oct. 498/1 These abnormal cocci have been termed ‘persisters’, to denote their power of surviving in the presence of sufficient penicillin to be lethal for the normal forms. 1949E. Chain et al. in H. W. Florey et al. Antibiotics II. xxxv. 1143 The proportion of persisters in cultures of staphylococci is not constant, and the factors governing their numbers are not yet fully understood. 1970Jrnl. Med. Microbiol. III. 669 Another type of persister is a cell in a non-replicating phase on which the antibiotic cannot act because of the absence of cell-wall synthesis. 1977Lancet 15 Oct. 822/2 Electron microscopy was the only technique to demonstrate successfully the presence of small numbers of bacterial persisters in the vegetations of this treated case of streptococcal endocarditis. |