| 释义 |
phenethicillin Pharm.|fəˌnɛθɪˈsɪlɪn|
[f. phen- + ethyl + penicillin.]
The compound 6-(2-phenoxypropionamido)penicillanic acid, C17H20N2O5S, which is a semi-synthetic penicillin active when given by mouth and is usu. employed in the form of the white, crystalline, potassium salt.
1960Brit. Med. Jrnl. 1 Oct. 994/2 When phenethicillin (6-(α-phenoxypropionamido)penicillanic acid) was marketed as ‘broxil’, it was claimed that this preparation would give blood levels at least equal to those after intramuscular injection of corresponding doses of penicillin G. 1965G. T. Stewart Penicillin Group of Drugs iii. 25 In scientific medical circles, the advent of phenethicillin as the first offspring of the new biosyntheses was something of an anticlimax. Ibid. iv. 34 As prepared at present, phenethicillin is a racemic mixture containing 55–75% of the l-isomer and 25–45% of the d-isomer. 1970Daily Tel. 23 Oct. 13/3 The first semi-synthetic penicillin, phenethicillin, introduced in 1959, became widely used for the infections treated by family doctors. |