| 释义 |
phosphatide Biochem.|ˈfɒsfətaɪd|
Also † -id.
[f. phosphate + -ide.]
Formerly = phospholipid; now esp. a fatty acid ester of glycerol phosphate in which a nitrogen base is linked to the phosphate group.
1884J. L. W. Thudichum Treat. Chem. Constitution Brain i. 4 According to the result of this revision the phosphorised substances [in the brain] are not glycerides at all, as commonly defined, and have nothing in common with fats considered as glycerides, except that some of them contain fatty acids also present in fats... In accordance with this new knowledge, I have termed the phosphorised substances phosphatides, that is to say, substances which are similar to (but not by any means identical with) phosphates, on the assumption that their basal or principal joining radicle is that of phosphoric acid and that in this acid one, two, or three molec[u]les of hydroxyl may be replaced by radicles of alcohols, acids, or bases. 1910[see phospholipin]. 1918[see heparin]. 1921B. Harrow Vitamines 43 A number of very complicated substances—the phosphatids—are found in larger quantities in the brain than in other parts of the body. 1927[see phospholipin]. 1944L. F. & M. Fieser Org. Chem. xix. 490 In the more active tissues (brain, liver, kidney, etc.) they [sc. fats] usually occur in a form more complex than depot fats, which are mainly glycerides... These fats can be divided into two classes, phosphatides and cerebrosides. The former on hydrolysis yield fatty acids, a nitrogenous base, phosphoric acid, and usually glycerol. 1951H. J. Deuel Lipids I. i. 4 Phospholipids or Phosphatides. The former term is most generally employed in the United States while the latter one is favored in English and German literature. 1953Fruton & Simmonds Gen. Biochem. xxii. 509 Evidence has been presented for the occurrence, in the..brain, of a phosphatide that contains inositol. 1954A. White et al. Princ. Biochem. v. 87 The next large class of lipids..is the phospholipids, more usually called phosphatides... The members of this group all contain a nitrogenous base. 1968Ibid. (ed. 4) iv. 69 The larger groups of naturally occurring phospholipids are termed phosphatides. |