| 释义 |
ˈplasma cell Histology.
Also plasma-cell.
[tr. G. plasmazelle (W. Waldeyer 1875, in Arch. f. mikrosk. Anat. XI. 189; also P. G. Unna 1891, in Monatschr. f. prakt. Dermatol. 1 Apr. 304): see plasma and cell n.1]
†a. A name given to a type of cell found in connective tissue. Obs.
b. A cell now recognized as the chief source of antibodies which is found in lymphoid tissue and at sites of chronic inflammation, and which has a strongly basophilic cytoplasm containing an extensive rough-surfaced endoplasmic reticulum and a usually eccentric nucleus. Cf. plasmacyte.
1888Rolleston & Jackson Anim. Life 115 Edible Snail... The connective tissue consists of plasma-cells, a matrix, and fibrils. 1895Jrnl. R. Microsc. Soc. 613 Waldeyer's plasma-cells correspond in staining reactions to Ehrlich's Mastzellen, but not to Unna's ‘plasma-cells’, and Waldeyer proposes to give up his use of the term as applied to normal elements of connective tissue. The cells he described as ‘plasma-cells’ are Ehrlich's Mastzellen and eosinophilous cells. 1904Brit. Med. Jrnl. 10 Sept. 586 In addition to these, we have the so-called plasma cells. 1906Jrnl. Amer. Med. Assoc. 20 Oct. 1272/2 The intimæ of the smaller arteries are lifted or completely dissected off by an exudate composed chiefly of cells of the lymphocyte series, among which are examples of the typical plasma cell. 1929Amer. Jrnl. Ophthalm. XII. 731/1 In 1875 Waldeyer applied the name of plasma cell to a poorly differentiated type of wandering cell which he found in chronically inflamed connective tissue. 1940Acta Med. Scand. CIII. 569 When Waldeyer..used the term plasma cell in 1875, he elected to do so not because he thought these cells secreted part of the plasma, but because of the abundant protoplasm. He made use of the term plasma cell to designate a number of different cells rich in protoplasm, but in subsequent works, especially those of Unna..and Marschalko.., the use of the name was restricted to the cell that is now known as the plasma cell: a cell rich in protoplasm, with eccentrically placed nucleus, relatively small, round or oval, with five to eight bands of chromatine extending from the centre like the spokes of a wheel; around the nucleus is a lighter zone, whilst the abundant protoplasm is otherwise dark, basophile. 1960New Biol. XXXI. 100 Absolute proof that plasma cells make antibody was furnished by an ingenious and elegant technique devised by Dr. A. H. Coons. 1968Passmore & Robson Compan. Med. Stud. I. xvi. 5/1 Plasma cells are found where foreign proteins are likely to gain entrance to the body, e.g. beneath the epithelial membranes lining the respiratory and alimentary tracts. 1975Lancet 3 May 1031/2 The plasma-cell is one of the effector cells of the B-lymphocyte system.
Hence plasma-celled a., composed of plasma cells; plasmaˈcellular a. (also plasmo- and as two words), of or pertaining to plasma cells.
1929Jrnl. Path. & Bacteriol. XXXII. 293 (heading) Two cases of myelomatosis: (1) Diffuse plasma-celled (2) with tumour-like nodules and visceral lesions. 1947Nature 12 Apr. 499/1 (heading) Plasma cellular reaction and its relation to the formation of antibodies in vitro. 1948R. A. Willis Path. Tumours l. 787 The multi⁓nucleated cells of plasma-celled and other myelomas are of no special histogenetic significance. 1957Jrnl. Amer. Med. Assoc. 4 May 20/2 In the broadest sense of the term this plasmocellular barrier may be called an immune process. 1971Biol. Abstr. LII. 6201/2 The ultrastructure of plasmacellular paracrystalline inclusions, detected in the sternal marrow of a patient with type k micromolecular myeloma was studied. |