| 释义 |
plasmoblast Histology.|ˈplæzməʊblɑːst, -æ-|
[f. plasmo- + -blast.]
The precursor of a plasmacyte. †a. (See quot.; cf. plasmocyte a.) Obs.
1897G. Eisen in Proc. Calif. Acad. Sci. (Zool.) I. 16 The polar accumulations must, therefore, be considered as something entirely separate from the balance of the cytoplasm; they, in fact, give rise to the plasmocytes, and may, therefore, appropriately be called plasmocytoblasts, or for the sake of brevity, plasmoblasts.
b. Also plasmablast. [a. G. plasmoblast (S. Moeschlin 1940, in Helv. Med. Acta VII. 231).] An immature plasma cell. Cf. plasmacyte.
1942Amer. Jrnl. Anat. LXX. 485 Moeschlin believes that some of the youngest lymphoid reticular cells begin to assume plasma cell characters, and that beginning with this ‘plasmoblast’ there is a developmental sequence of stages leading to the mature plasma cell, and that this sequence is probably independent of the lymphocytic line. 1949Jrnl. Exper. Med. XC. 165 Maturation of plasmoblasts to plasma cells was associated..with reduction in the size of the nucleus and disappearance of the PNA [sc. pentose nucleic acid] in the nucleolus. 1959M. Burnet Clonal Selection Theory of Acquired Immunity vii. 113 In lymph nodes the first small foci of plasmoblasts appeared in a perivascular situation near the arterioles of the medullary cords. 1973R. I. Weed tr. M. Bessis's Living Blood Cells & their Ultrastructure vii. 521/1 Plasmablast. On a smear, this cell measures 15 to 20 microns in diameter. Its principal characteristic is the profound basophilia of its cytoplasm.
Hence plasmoˈblastic a.
1970Jrnl. Nuclear Med. XI. 599/2 EH was a 54-year-old W.F. with plasmoblastic multiple myeloma with widespread skeletal involvement, [etc.]. 1975Biol. Abstr. LIX. 6033/1 In lymphoblastic and plasmoblastic acute leukemias pathological cells were capable of synthesizing various Ig classes. |