| 释义 |
prototropy Chem.|prəʊˈtɒtrəpɪ, ˈprəʊtəʊtrɒpɪ|
[f. proton + Gr. τροπή turn, turning.]
Tautomerism in which the forms differ only in the position of a proton; migration of a proton from one part of a molecule to another.
1923T. M. Lowry in Jrnl. Chem. Soc. CXXIII. 828 Prototropy, or the reversible change of protomers, which differ from one another in the position of a proton or hydrogen nucleus. 1953C. K. Ingold Structure & Mechanism in Org. Chem. v. 219 Proton migration is considered always to depend on proton-transfer processes..and is of such outstanding importance, that it is usually designated by the special name prototropy. 1964N. G. Clark Mod. Org. Chem. xv. 296 The behaviour of ethyl acetoacetate is another example of the phenomenon of tautomerism, in particular of prototropy.
Hence protoˈtropic a., of, pertaining to, or exhibiting prototropy.
1925Jrnl. Chem. Soc. CXXVII. 1382 Prototropic changes, which involve only the migration of a proton, are catalysed both by acids and by alkalis, like the hydrolysis of an ester. 1947Nature 11 Jan. 68/1 Dislocation of α-hydrogen in glutamic acid can be interpreted as due to reversible condensation of the amino-group with the carbonyl in the prosthetic component of aminopherase to form a prototropic system. 1953C. K. Ingold Structure & Mechanism in Org. Chem. x. 579 When 2-hydroxypyridine, or α-pyridone, as it is usually named after its prototropic tautomer, is alkylated..the formed quaternary ammonium ion passes into its anhydro-base, the N- alkyl-α-pyridone. 1976Nature 6 May 15/1 Ganellin showed that dynamic structure-activity relationships are capable of analysing quite complex situations, such as relative ionic populations in a prototropic equilibrium mixture. |