| 释义 |
rotamer Chem.|ˈrəʊtəmə(r)|
[f. rotational a. + -mer.]
Any of a number of distinct conformations of a molecule which can be interconverted by rotation of part of the molecule about a particular bond; a rotational isomer.
1963Chem. & Industry 29 June 1086/1 The single sharp N-methyl signal indicates magnetic averaging of signals and hence very rapid rotamer interconversion even at low temperatures. 1969Jrnl. Chem. Soc. B. 1019/2 The near temperature-invariance of the n.m.r. spectrum over the range studied could be the consequence either of one minimum-energy rotomer being strongly preferred, or of insufficient difference in magnetic shielding at N-methyl for different rotamers. 1976Nature 26 Aug. 780/1 The analysis of the side-chain rotamer population..shows that the Met, Phe, and Tyr side chains favour one of the two possible trans-gauche rotamers, but for each of these residues all three rotamers have significant populations. |