| 释义 |
psychotomimetic, a. and n.|saɪˌkɒtəʊmɪˈmɛtɪk, -maɪˈmɛtɪk|
Also † psychoso-.
[Orig. formed as psychosomimetic, f. psychosis + -o + mimetic a., and later altered to match psychotic a.]
A. adj. Having an effect on the mind orig. likened to that of a psychotic state, with abnormal changes in thought, perception, and mood and a subjective feeling of an expansion of consciousness; of or pertaining to a drug with this effect.
1956R. W. Gerard in Neuropharmacology: Trans. 2nd Conf., 1955 132 Let us at least agree to speak of ‘so-called’ psychoses when we are dealing with them in animals... Along that same line, I have liked a term which I have been using lately—‘psychosomimetic’—for these agents instead of ‘schizophrenogenic’. 1957Neuropharmacology: Trans. 3rd Conf., 1956 205 (heading) Effects of psychosomimetic drugs in animals and man. 1957H. Osmond in Ann. N.Y. Acad. Sci. LXVI. 417 The designation ‘psychotomimetic agents’ for those drugs that mimic some of the mental aberrations that occur in the psychoses had been suggested by Ralph Gerard and seemed especially appropriate. 1958M. Jarvik in H. H. Pennes Psychopharmacology ix. 204 They have been called psychoso- or psychotomimetic, psychotherapeutic, tranquilizing, ataraxic,.. or, as a general class, psychochemical, neurotropic,..and a number of other names. 1962Henderson & Gillespie Text-bk. Psychiatry xi. 258 The hallucinogenic (or psychotomimetic) drugs most often employed have been mescaline and lysergic acid (LSD 25). 1964D. F. Downing in M. Gordon Psychopharmacological Agents I. xiii. 562 Psilocybin and psilocin produce a psychotomimetic effect in man..which is similar to that produced by mescaline or LSD-25. 1967Sunday Mail (Brisbane) 27 Aug. 5/1 In the field of drugs, a medical friend says that if you want another term for psychedelics you could call them..psychotomimetic. 1970E. Goode Marijuana Smokers vii. 172 The general psychotomimetic questions include: ‘Is your skin sensitive?’ ‘Are you happy?’ ‘Are colors brighter?’ 1970D. H. Efron Psychotomimetic Drugs 5 The use of these psychotomimetic substances in ancient times was either for religious, ceremonial or recreational purposes. 1975Brimblecombe & Pinder Hallucinogenic Agents i. 3 It has been pointed out several times..that there are well-defined differences between mental states induced by the majority of psychotomimetic drugs and those encountered in mental illness.
B. n. A psychotomimetic drug.
1957Ann. N.Y. Acad. Sci. LXVI. 418 We are using Gerard's term ‘psychotomimetics’ generally for compounds that have been called schizogens, psychotica, psychotogens, phantastica, hallucinogens and elixirs. If one believes that the importance of these compounds lies in their capacity to mimic the mental illnesses called psychoses, psychotomimetics would be the choice. 1970A. T. Shulgin in D. H. Efron Psychotomimetic Drugs 25 Ibogaine..is another example in the family of psychotomimetics, with complex structures and no resemblance to known metabolic materials. 1974M. C. Gerald Pharmacol. xvi. 299 The psychotomimetics (hallucinogens) such as LSD or mescaline produce profound alterations in behavior.
Hence psyˌchotomiˈmetically adv.
1963Tetrahedron XIX. 2073 Hashish (marihuana), the psychotomimetically active resin of the female flowering tops of Cannabis sativa L. 1970L. Harmon in D. H. Efron Psychotomimetic Drugs 349 So for Dan's N.I.M.H. hospitality (T'was psychotomimetically hip) Great thanks for new lights on mentality And a most unforgettable TRIP. 1973R. Mechoulam Marijuana p. xiii, The structure of only one [cannabinoid], the psychotomimetically inactive cannabinol, had been fully elucidated. |