| 释义 |
Schotten–Baumann, n. Organic Chem.|ˈʃɒtən ˈbaʊmən|
The names of Carl Ludwig Schotten (1853–1910) and Eugen Baumann (1846–96), German chemists, used attrib. (esp. as Schotten–Baumann method, Schotten–Baumann reaction) and occas. in the possessive with reference to a type of reaction in which a primary or secondary amine reacts with an acid halide in basic aqueous solution to form an amide; also used with reference to analogous reactions involving primary and secondary alcohols.
1895Jrnl. Chem. Soc. LXVIII. i. 139 A convenient modification of the Schotten–Baumann method is also suggested. 1902J. B. Cohen Theoret. Org. Chem. xxxiv. 468 A simple and rapid method for preparing small quantities of esters..is that known as Schotten–Baumann's reaction. 1920A. K. Macbeth Org. Chem. xxv. 214 The operation is carried out by shaking the substance with benzoyl chloride and dilute alkali... The is known as the Schotten–Baumann reaction. 1935P. H. Groggins Unit Processes in Org. Synthesis x. 514 As the esters formed by the Schotten–Baumann method are insoluble in the aqueous alkali, they are readily separated. 1958Packer & Vaughan Mod. Approach to Org. Chem. xxiv. 788 An improvement on the original Schotten–Baumann method is the use of pyridine in place of aqueous alkali. 1964N. G. Clark Mod. Org. Chem. xxiii. 485 ‘Benzoylation’ is..often used for characterizing amines, and may also be performed by a Schotten–Baumann technique. 1981J. W. Buttle et al. Chemistry (ed. 4) xxi. 461 The more usual derivative for amines, however, is the benzenecarboxamide, prepared from benzoyl chloride (the Schotten–Baumann reaction). |