| 释义 |
scleromyxœdema Path.|ˌsklɪərəʊmɪksiːˈdiːmə|
Also -myxedema.
[ad. G. skleromyxödem (H. H. Gottron 1954, in Arch. f. Dermatol. u. Syphilis CXCIX. 71): see sclero- and myxœdema s.v. myxo-.]
A disease characterized by the extensive proliferation of fibroblasts and deposition of mucopolysaccharides in the skin, causing distortions of the features and lichenous eruptions.
1964Arch. Dermatol. LXXXIX. 446/1 Lichen myxedematosus, also known as..scleromyxedema, is a well-known clinical entity. 1968R. J. Cairns in A. Rook et al. Textbk. Dermatol. II. lv. 1621/2 A variant of lichen myxoedematosus is scleromyxoedema..—the Arndt-Gottron syndrome—in which diffuse thickening of the skin underlies the papules... The features may be distorted by the exaggeration of the facial ridges and flexion of the fingers may be limited. 1977Lancet 4 June 1208/2 Ten years previously this patient has been treated for scleromyxœdema..with melphalan. |