| 释义 |
pyridoxamine Biochem.|pɪrɪˈdɒksəmiːn|
[f. as next + amine.]
One of the active forms of vitamin B6 (related to pyridoxine by replacement of the 4-hydroxymethyl group by an aminomethyl group), which is usu. present in mammals as the phosphate ester and is a co-enzyme in protein metabolism. Cf. pyridoxine.
1944E. E. Snell in Jrnl. Biol. Chem. CLIV. 315 (caption) Pyridoxamine. 1944[see pyridoxal]. 1950Thorpe's Dict. Appl. Chem. (ed. 4) X. 316/2 Schlenk and Fisher..working with the glutamic-aspartic transaminase system from pig-heart, have suggested that the reversible interconversion of pyridoxal and pyridoxamine in the prosthetic group forms the basis of the enzyme system. 1961[see pyridoxine]. 1966[see pyridoxal]. 1968J. Marks Vitamins in Health & Dis. 94/2 The B6 group are rapidly converted in the body into the co-enzymes pyridoxal phosphate and pyridoxamine phosphate... These co-enzymes play an essential role in protein metabolism. 1970R. W. McGilvery Biochem. vi. 120 The substituted pyridine ring of pyridoxal phosphate..cannot be synthesized by vertebrates, and its dietary precursors are lumped together as vitamin B6, which includes pyridoxal, pyridoxamine, and the corresponding alcohol, pyridoxine. |