myx·e·de·ma or myx·oe·de·ma 
(mĭk′sĭ-dēmə)
(mĭk′sĭ-dēmə)n.
A disease caused by decreased activity of the thyroid gland in adults and characterized by dry skin, swellings around the lips and nose, mental deterioration, and a subnormal basal metabolic rate.
myx′e·dema·tous (-dĕmə-təs, -dēmə-), myx′e·demic (-dĕmĭk) adj.