1. A conflict, especially between the protagonist and antagonist in a work of literature.

2. The part of an ancient Greek drama, especially a comedy, in which two characters engage in verbal dispute.

3. A test of will; a conflict: "Freud's originality stemmed from his aggression and ambition in his agon with biology" (Harold Bloom).

4. A contest in ancient Greece, as in athletics or music, in which prizes were awarded.