Synonyms: perplex, mystify, bewilder, confound, puzzle
These verbs mean to cause bafflement or confusion. Perplex stresses uncertainty or anxiety, as over reaching an understanding or finding a solution: "No subject at the Philadelphia convention had perplexed the delegates more than the mode of choosing the president" (Susan Dunn).
Mystify implies something inexplicable by conventional understanding: "Galileo was mystified by the disappearance of the two smaller bodies accompanying Saturn along its orbit" (Eric Burgess).
Bewilder emphasizes extreme mental confusion: " We human beings are ... bewildered when trying to imagine a world with more than three dimensions" (Paul Davies).
To confound is to confuse and astonish: God hath chosen the foolish things of the world to confound the wise (I Corinthians 1:27).
Puzzle suggests difficulty in solving or interpreting something: "The poor creature puzzled me once ... by a question merely natural and innocent" (Daniel Defoe).