As a result, in order to move past each other in an extremely crowded environment, they are forced to modify their behavior.

The crowded environment of the cytosol can accelerate the folding process, since a compact folded protein will occupy less volume than an unfolded protein chain.

And more crowded environments allow for more interactions.

Animals kept in crowded environments can easily spread these diseases.

For instance, the evolution of a galaxy in time depends on its location in the cosmos: galaxies in empty regions experience strikingly different histories from those inhabiting crowded environments.