Unfortunately, several participants in the study had to discontinue treatment because of side effects such as excessive daytime sleepiness or orthostatic hypotension.

Some patients adjust to the treatment within a few weeks, others struggle for longer periods, and some discontinue treatment entirely.

He has cancer and has decided to discontinue treatment.

Individuals who receive a higher dose of psychiatric medication than needed may discontinue treatment because of side effects, or they may develop toxic levels that lead to serious complications.

Further, patients who discontinue treatment are more likely to be characterized as chronic patients, resulting in over-utilization of services, up to twice as much as appropriate terminators.