If the patches aren't doing the job, they may be able to increase the dose or try you on an alternative.

Doctors can increase his dose when his condition worsens, but he will need to switch to more expensive treatments as he gets older.

So dairymen began increasing the dose of formaldehyde, seeking to keep their product “fresh” for as long as possible.

I know that a lot of people feel they have to keep increasing their dose to get the same effect.

If the 40mg dose isn't strong enough to reduce cholesterol, try a lower dose of a more powerful statin (atorvastatin or rosuvastatin) rather than increasing the dose of simvastatin.