This leads to release of pro-inflammatory cytokines and nitric oxide, which may lead ultimately to septic shock depending on the strength of response.

First collisions are between continents and island arcs, but lead ultimately to continent-continent collisions.

It led ultimately to the creation of kidney exchanges, where donors could save a relative even where there was no biological match.

But they feel that they must adopt utilitarian ethics, justifying everything on the basis that it leads ultimately to the greatest happiness of the greatest number of shareholders.

It led ultimately to the remarkable resurgence of interest in string theory that has continued to this day.