figurative and in extended use: weakened or disempowered.

Made pale or faint; enfeebled. Obsolete.

Weakened, enfeebled.

Rendered physically weak; deprived of courage or confidence; (also) unsettled.

Impeded or weakened; (also) blunt. Obsolete. rare.

Made feeble, weakened.

(un-, prefix1 affix 2.)

Of a person. Originally North American. Shaky, weakened; unnerved; unwell.