Actively evil, deadly, dire, pernicious, destructive, fatal, cruel, tormenting.

Full of malign, deadly, or noxious influence; pernicious, destructive, noxious, injurious, mischievous, malignant. Morally.

figurative. Morally or spiritually hurtful or injurious; pernicious. Obsolete.

Morally or socially injurious, noxious, or dangerous; grievous, ‘pestilent’. Obsolete.

Morally or socially harmful; pernicious.

Harmful or dangerous to religious, moral, or social order; noxious, pernicious.

Of a thing, action, intent, etc.: causing or likely to cause harm, esp. in a gradual or insidious manner; dangerous, destructive; evil. Also in…

Morally or socially harmful; pernicious; repulsive, abhorrent.

Morally or socially harmful; pernicious; abhorrent. Now rare.

Now archaic and rare. Of the nature of or relating to bubonic plague or any other plague-like disease; pestiferous, pestilential, pernicious. Also…

Having an adverse effect on the state or condition of a person, society, etc.; mentally, emotionally, or morally damaging.

(un-, prefix1 affix 4.)

= pernicious, adj.1

Not edifying.

(un-, prefix1 affix 4.)

Not having a healthy mental or social influence or effect.

(un-, prefix1 affix 1.)