Originally: affliction, trial. Subsequently also: labour, toil.

Trouble, hardship; = derf, n.

Misery, distress, hardship; adversity, poverty.

Adverse fortune, condition, or circumstance; a state opposed to well-being or prosperity; misfortune, distress, difficulty, hardship.

Trouble, tribuation, hurt.

Trouble, affliction; an instance of this. Obsolete.

Hardship, trouble, distress; harm, mischief, injury.

The state of being afflicted; misery, distress.

Hardship, adversity; affliction, suffering. Cf. distress, n. 2. Obsolete.

Trouble, affliction.

Grievous state; affliction, misery. Obsolete.

The condition or fact of being annoyed, troubled, or harmed; irritation, vexation, distress.

The condition of being unfortunate; misfortune, bad luck.

Also more fully bitter aloe(s). figurative. Bitter experiences, occurrences, etc.; bitterness. Usually in plural (with singular agreement).

= affliction, n.

Affliction, adversity. Obsolete.

The state of being afflicted; distress.

In immaterial applications of sense 9a. Pressure or exigency that severely taxes the strength, endurance, or resources of a person or thing, or that…

A condition of being beset by enemies.

In Nigeria: trouble, affliction, calamity; (also) inconvenience, fuss, bother, palaver.

A bad time; misfortune, hardship, difficulty.